She married Isaac Mitchell 1823. (Melanie Ayres Merryweather, Genealogy of the Henry Family) Isaac was the
son of John Pope Mitchell and Mary "Polly" Purnell.
Isaac died 1829. In 1835, Stephen Purnell named John Mitchell as trustee to Isaac's three sons. Isaac was not named in his father's
will but was called son and named executor in his mother's will. (research of Vernon L. Skinner; Melanie Ayres Merryweather, Genealogy of
the Henry Family, p. 11)
Isaac Mitchell and Sally Henry had the following children:
Lemuel6 Mitchell. In 1826, Polly Mitchell called him her grandson, son of
Isaac. In 1834, Nancy Purnell named Lemuel as son of her nephew Isaac.